What is the Role of Proteostasis in Cellular Function?
Proteostasis is vital for maintaining cellular function by ensuring that proteins are correctly synthesized, folded, and localized. Correctly folded proteins are essential for executing cellular processes such as signal transduction, cell cycle regulation, and metabolism. Disruption in proteostasis can lead to misfolded proteins, which may form aggregates that are toxic to cells and are implicated in diseases like Alzheimer's, Parkinson's, and Huntington's.
