The TUNEL assay (Terminal deoxynucleotidyl transferase dUTP nick end labeling) is a widely used technique in Cell Biology to detect DNA fragmentation resulting from apoptosis. It specifically labels the 3'-OH ends of DNA breaks, which are abundant during this type of programmed cell death. By providing a visual representation of apoptotic cells, the TUNEL assay is an essential tool for researchers studying cell death and related processes.
