Induced pluripotent stem cells (iPSCs) are a type of pluripotent stem cell that are generated directly from adult cells. The process of creating iPSCs involves reprogramming differentiated cells, such as fibroblasts, to an embryonic-like pluripotent state through the introduction of specific transcription factors. This remarkable achievement was first reported in 2006 by Shinya Yamanaka and his team, marking a significant breakthrough in stem cell research.