NADH is a key player in cellular respiration, particularly in the electron transport chain (ETC). In the mitochondria, NADH donates electrons to Complex I of the ETC. This transfer initiates a series of redox reactions that ultimately lead to the generation of a proton gradient across the inner mitochondrial membrane. The energy from this proton gradient is used by ATP synthase to convert ADP into ATP, the primary energy currency of the cell.
