Agonistic antibodies are specialized antibodies that can bind to receptors on cell surfaces and activate them, much like natural ligands. Unlike antagonistic antibodies, which inhibit receptor activity, agonistic antibodies trigger a receptor's signaling cascade, often resulting in cellular responses such as proliferation, differentiation, or apoptosis. These antibodies are typically engineered to have high specificity and affinity for their target receptors, making them powerful tools for both research and clinical applications.