Neurons communicate through electrical and chemical signals. The process begins with the generation of an action potential, an electrical impulse that travels along the axon of the neuron. Once the action potential reaches the end of the axon, it triggers the release of neurotransmitters into the synaptic cleft. These chemical messengers cross the synapse and bind to receptors on the adjacent neuron, initiating a response. This synaptic transmission is crucial for the propagation of signals throughout the nervous system.