What are the Phases of the Pentose Phosphate Pathway?
The PPP consists of two distinct phases: the oxidative phase and the non-oxidative phase.
1. Oxidative Phase: This phase generates NADPH and involves the oxidation of glucose-6-phosphate. Key enzymes in this phase include glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase.
2. Non-Oxidative Phase: This phase is responsible for the synthesis of ribose-5-phosphate and involves sugar phosphate interconversions. Important enzymes include transketolase and transaldolase.
