The smooth ER has a variety of functions including:
Lipid synthesis: It is the site of phospholipid and cholesterol synthesis, which are essential for cell membrane formation. Detoxification: It metabolizes potentially harmful substances, such as drugs and toxins, thereby detoxifying the cell. Carbohydrate metabolism: It is involved in the metabolism of carbohydrates, including the conversion of glucose-6-phosphate to glucose. Calcium storage: It stores calcium ions, which are important for various cellular processes, including muscle contraction and signal transduction.