The process involves isolating individual cells, extracting their genetic material, and then sequencing it. Various methods exist for cell isolation, such as microfluidics, fluorescence-activated cell sorting (FACS), and laser capture microdissection (LCM). After isolation, the genetic material is amplified to obtain sufficient quantities for sequencing. Technologies like RNA-seq and ATAC-seq are commonly used to analyze gene expression and chromatin accessibility, respectively.
