Researchers use various techniques to study oncogenes, including:
Gene knockout and knock-in models: These genetic engineering techniques allow scientists to investigate the role of specific oncogenes in cancer development by selectively deleting or introducing mutations in them. Cell culture studies: Cancer cell lines with known oncogene alterations are used to study the effects of oncogene activation on cellular behavior and to test potential therapeutic interventions. Animal models: Genetically engineered mice and other animals are used to study the in vivo effects of oncogene activation and to evaluate the efficacy of targeted therapies.
