How are Growth Signals Targeted in Cancer Therapy?
Targeting aberrant growth signaling pathways is a key strategy in cancer therapy. Therapies include:
Monoclonal Antibodies: Drugs like trastuzumab target HER2 receptors in breast cancer. Tyrosine Kinase Inhibitors: Agents like imatinib inhibit BCR-ABL fusion proteins in chronic myeloid leukemia. mTOR Inhibitors: Drugs such as rapamycin target the mTOR pathway, which is often dysregulated in cancer.