Guanine Nucleotide Exchange Factors (gefs) - Cell Biology

Relevant Publications

Targeting guanine nucleotide exchange factors for novel cancer drug discovery.

Issue Release: 2024

Efficacy and delivery strategies of the dual Rac/Cdc42 inhibitor MBQ-167 in HER2 overexpressing breast cancer.

Issue Release: 2024

The GTPase activating protein Gyp7 regulates Rab7/Ypt7 activity on late endosomes.

Issue Release: 2024

DENND6A links Arl8b to a Rab34/RILP/dynein complex, regulating lysosomal positioning and autophagy.

Issue Release: 2024

The RhoGAP RRC-1 is required for the assembly or stability of integrin adhesion complexes and is a member of the PIX pathway in muscle.

Issue Release: 2024

Real-Time Monitoring of RAS Activity Using In Vitro and In-Cell NMR Spectroscopy.

Issue Release: 2024

The lipid flippase ATP8A1 regulates the recruitment of ARF effectors to the Trans-Golgi Network.

Issue Release: 2024

AGS3-based optogenetic GDI induces GPCR-independent Gβγ signaling and macrophage migration.

Issue Release: 2024

New Mechanisms Underlying Oncogenesis in Dbl Family Rho Guanine Nucleotide Exchange Factors.

Issue Release: 2024

Point mutations in Arf1 reveal cooperative effects of the N-terminal extension and myristate for GTPase-activating protein catalytic activity.

Issue Release: 2024

ARHGEF5 binds Drebrin and affects α-tubulin acetylation to direct neuronal morphogenesis and migration during mouse brain development.

Issue Release: 2024

Decreased Tiam1-mediated Rac1 activation is responsible for impaired directional persistence of chondrocyte migration in microtia.

Issue Release: 2024

Implication of Rac1 GTPase in molecular and cellular mitochondrial functions.

Issue Release: 2024

Roles of G proteins and their GTPase-activating proteins in platelets.

Issue Release: 2024

Understanding P-Rex regulation: structural breakthroughs and emerging perspectives.

Issue Release: 2024

RhoGDI1 regulates cell-cell junctions in polarized epithelial cells.

Issue Release: 2024

Regulation of ROP GTPase cycling between active/inactive states is essential for vegetative organogenesis in Marchantia polymorpha.

Issue Release: 2024

Neuroprotection and axon regeneration by novel low-molecular-weight compounds through the modification of DOCK3 conformation.

Issue Release: 2023

Insights into the role of the membranes in Rab GTPase regulation.

Issue Release: 2023

DENND2B activates Rab35 at the intercellular bridge, regulating cytokinetic abscission and tetraploidy.

Issue Release: 2023

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