Eukaryotic Ribosome Scanning - Cell Biology

Relevant Publications

Host-like RNA Elements Regulate Virus Translation.

Issue Release: 2024

Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo.

Issue Release: 2024

Leaky ribosomal scanning enables tunable translation of bicistronic ORFs in green algae.

Issue Release: 2024

Critical -parameters influence STructure assisted RNA translation (START) initiation on non-AUG codons in eukaryotes.

Issue Release: 2024

A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer.

Issue Release: 2024

Deciphering the regulatory landscape of natural yeast Transcript Leaders.

Issue Release: 2024

Structural basis for translational control by the human 48S initiation complex.

Issue Release: 2024

The Roles of eIF4G2 in Leaky Scanning and Reinitiation on the Human Dual-Coding POLG mRNA.

Issue Release: 2023

The molecular basis of translation initiation and its regulation in eukaryotes.

Issue Release: 2023

Exploring the Targeting Spectrum of Rocaglates Among eIF4A Homologs.

Issue Release: 2023

Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo.

Issue Release: 2023

PRRC2 proteins impact translation initiation by promoting leaky scanning.

Issue Release: 2023

DAP5 Binding to the FGF-9 mRNA 5\' UTR is Structurally-Dependent.

Issue Release: 2022

Specific Mechanisms of Translation Initiation in Higher Eukaryotes: The eIF4G2 Story.

Issue Release: 2022

Distance-dependent inhibition of translation initiation by downstream out-of-frame AUGs is consistent with a Brownian ratchet process of ribosome scanning.

Issue Release: 2022

Stepwise assembly of the eukaryotic translation initiation factor 2 complex.

Issue Release: 2022

Zotatifin, an eIF4A-Selective Inhibitor, Blocks Tumor Growth in Receptor Tyrosine Kinase Driven Tumors.

Issue Release: 2021

Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.

Issue Release: 2021

Bi-directional ribosome scanning controls the stringency of start codon selection.

Issue Release: 2021

1-Aminomethyl SAR in a novel series of flavagline-inspired eIF4A inhibitors: Effects of amine substitution on cell potency and in vitro PK properties.

Issue Release: 2021

How Do Cellular Therapies Aim to Treat Diabetes?

What Role Do Cell Signaling Pathways Play?

How is the Golgi Apparatus related to Disease?

What are Growth Signals?

What Are Organelles?

What is Cellular Respiration?

What are the Consequences of Necrosis?

How Does the Cytoskeleton Interact with Other Cellular Structures?

What are the Key Steps in Molecular Cloning?

How is NADH measured in the laboratory?

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