Macroautophagy: The most common form, involving the formation of autophagosomes that engulf large cellular structures. Microautophagy: The direct invagination of the lysosomal membrane to engulf small amounts of cytoplasm. Chaperone-mediated autophagy (CMA): The selective degradation of proteins that recognize a specific motif and are translocated across the lysosomal membrane via chaperone proteins.