Alfred Lewis Goldberg - Cell Biology

Author Information

Alfred Lewis Goldberg is a renowned researcher affiliated with the Department of Cell Biology at Harvard Medical School, Boston, MA 02115. His extensive work in the field of cell biology has significantly advanced our understanding of protein degradation and proteostasis mechanisms.

Research Contributions

Alfred Lewis Goldberg has made substantial contributions to cell biology, particularly in the areas of proteasome function, protein degradation, and proteostasis. His research has elucidated mechanisms by which cells maintain protein quality control, with implications for understanding diseases like neurodegenerative disorders and cancer. Notably, his recent works include studies on the activation of 26S proteasomes, the role of cGMP in restoring proteasome function, and the sensitivity of multiple myeloma cells to heat shock. Additionally, his research on Mycobacterium tuberculosis ClpP1P2 protease function and the role of ubiquitin-like domains in proteasome activation has provided deeper insights into bacterial protein degradation mechanisms.

Aliases

Alfred Lewis Goldberg is known by various aliases, including A L Goldberg, A. L. Goldberg, Alfred L Goldberg, Alfred Goldberg, Alfred L. Goldberg, A Goldberg, A.l. Goldberg, and Alfred Lewis Goldberg.

Publication and Citation Metrics

Metric Value
Total Citation Count 83,874
H-index 150
Paper Count 462

Publications:

DOI: 10.1016/b978-0-12-819460-7.00025-6

Year: 2020

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