What is the Importance of Extrinsic Control in Stem Cell Differentiation?
Extrinsic factors are vital in guiding stem cell differentiation. The surrounding microenvironment, also known as the niche, provides extrinsic cues that direct stem cells to differentiate into specific cell types. These cues include soluble factors, cell-cell interactions, and mechanical signals, which together maintain stem cell pluripotency or drive differentiation.
