Cryo-EM has significantly advanced our understanding of cellular processes. For instance, it has been instrumental in elucidating the structure of the ribosome, understanding the mechanics of molecular motors, and visualizing the architecture of membrane proteins. Recent breakthroughs in cryo-EM technology have also led to the rapid determination of the structures of various SARS-CoV-2 proteins, aiding in the development of COVID-19 vaccines and therapeutics.