Jonathan L. Tilly - Cell Biology

Author Information

Jonathan L. Tilly is a prominent researcher in the field of cell biology, particularly focusing on aging and infertility research. He is currently affiliated with the Department of Biology at Northeastern University in Boston, Massachusetts. His work has significantly contributed to the understanding of germline stem cells and their role in female reproductive biology.

Research Contributions

Jonathan L. Tilly has made substantial contributions to the field of reproductive biology and stem cell research. His recent work includes optimizing workflows for identifying female germline or oogonial stem cells using single-cell RNA sequencing and exploring the dynamics of mitochondrial DNA mutations in germline cells. He has also worked on developing tools for high-resolution nucleic acid sequencing and analyzing third-generation sequencing data. His research aims to bridge the gap between stem cell biology and reproductive medicine, with an emphasis on understanding mechanisms that contribute to female reproductive aging.

Aliases

Throughout his career, Jonathan L. Tilly has published under various aliases, including J L Tilly, Jonathan Tilly, J. L. Tilly, J. Tilly, and Jonathan L Tilly. These variations may appear across different publications and databases.

Publication and Citation Metrics

Metric	Value
Citation Count	17,996
H-index	69
Paper Count	223

Publications:

Workflow optimization for identification of female germline or oogonial stem cells in human ovarian cortex using single-cell RNA sequence analysis.

DOI: 10.1093/stmcls/sxac015

Year: 2022

3GOLD: optimized Levenshtein distance for clustering third-generation sequencing data

DOI: 10.1186/s12859-022-04637-7

Year: 2022

Biomechanical Strain Promotes the Differentiation of Murine Oogonial Stem Cells.

DOI: 10.1089/scd.2021.0086

Year: 2021

Bi-phasic dynamics of the mitochondrial DNA mutation m.3243A>G in blood: An unbiased, mutation level-dependent model implies positive selection in the germline

DOI: 10.1101/2021.02.26.433045

Year: 2021

Nuclear DNA-encoded fragments of mitochondrial DNA (mtDNA) confound analysis of selection of mtDNA mutations in human primordial germ cells

DOI: 10.1101/2021.10.18.464832

Year: 2021

3GOLD: Optimized Levenshtein distance for clustering third-generation sequencing data

DOI: 10.21203/rs.3.rs-982478/v1

Year: 2021

Reproductive medicine at the crossroads of stem cell biology and big-data.

DOI: 10.1016/j.fertnstert.2021.06.042

Year: 2021

Estrogen regulation of germline stem cell differentiation as a mechanism contributing to female reproductive aging

DOI: 10.18632/aging.103080

Year: 2020

The obligate need for accuracy in reporting preclinical studies relevant to clinical trials: autologous germline mitochondrial supplementation for assisted human reproduction as a case study

DOI: 10.1177/2633494120917350

Year: 2020

LUCS: a high-resolution nucleic acid sequencing tool for accurate long-read analysis of individual DNA molecules

DOI: 10.18632/aging.103171

Year: 2020

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