Ian Dunham - Cell Biology

Author Information

Ian Dunham is a prominent researcher affiliated with several prestigious institutions including the Wellcome Sanger Institute, Open Targets, and the European Molecular Biology Laboratory (EMBL-EBI), all located at the Wellcome Genome Campus in the United Kingdom. His work is highly regarded in the fields of cell biology, genetics, and genomics.

Research Contributions

Ian Dunham has made significant contributions to the understanding of genetic associations and their implications in human health. His recent work includes integrative analyses of genome-wide association studies (GWAS) to uncover novel regulatory associations specific to various cell types. He has also explored the modulation of gene expression by immune disease variants in regulatory CD4+ T cells and identified potential drug targets for COVID-19 severity through Mendelian randomization studies. Furthermore, Dunham has been involved in initiatives like CACHE to benchmark computational methods for hit-finding and has contributed to defining a pleiotropy map of human cell biology.

Aliases

Ian Dunham is known by several aliases in academic publications, including "I Dunham" and "I. Dunham."

Publication and Citation Metrics

Metric	Value
Total Citation Count	45,189
H-index	69
Total Paper Count	251

Publications:

Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations

DOI: 10.1186/s13059-021-02560-3

Year: 2022

Immune disease variants modulate gene expression in regulatory CD4+ T cells

DOI: 10.1016/j.xgen.2022.100117

Year: 2022

Multi-Ancestry Mendelian Randomization of Omics Traits Revealing Putative Drug Targets of COVID-19 Severity

DOI: 10.2139/ssrn.4053476

Year: 2022

CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding

DOI: 10.26434/chemrxiv-2021-rzq4n

Year: 2021

CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding

DOI: 10.33774/chemrxiv-2021-rzq4n

Year: 2021

Network expansion of genetic associations defines a pleiotropy map of human cell biology

DOI: 10.1101/2021.07.19.452924

Year: 2021

The PROTACtable genome

DOI: 10.1038/s41573-021-00245-x

Year: 2021

A proteome-wide genetic investigation identifies several SARS-CoV-2-exploited host targets of clinical relevance

DOI: 10.1101/2021.03.15.21253625

Year: 2021

A proteome-wide genetic investigation identifies several SARS-CoV-2-exploited host targets of clinical relevance

DOI: 10.7554/eLife.69719

Year: 2021

An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci.

DOI: 10.1038/s41588-021-00945-5

Year: 2021

What are Some Common Cell Biology Disorders?

How is mitochondrial DNA different from nuclear DNA?

What is the Pathological Role of Alpha Synuclein?

What is Gene Expression?

What Are the Consequences of Excessive Apoptosis?

How is DNA Fragmentation Utilized in Research and Medicine?

What are the End Products of Glycolysis?

What are Checkpoint Inhibitors?

How do Hormones Affect Preterm Labor?

How Does PKU Affect Cellular Metabolism?

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