Alexander Scheffold - Cell Biology

Author Information

Alexander Scheffold is a researcher affiliated with the Department of Cellular Immunology at the Clinic for Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, located at Charitéplatz 1, 10117, Berlin, Germany. His work primarily focuses on cellular immunology and he has contributed significantly to the understanding of T cell biology and immune responses.

Research Contributions

Alexander Scheffold has made significant contributions to the field of immunology, particularly in the study of T helper cell biology and the role of metalloproteases such as ADAM10 in immune processes. His recent work includes exploring the molecular mechanisms underlying immune responses in diseases such as Crohn's disease and COVID-19. Notably, his research has identified novel T cell populations and characterized immune responses in various pathological conditions, advancing the understanding of immune system dynamics.

Aliases

Alexander Scheffold is also known by several aliases, including A Scheffold, A. Scheffold, and Alexa Scheffold.

Publication and Citation Metrics

Metric	Value
Total Citation Count	13,084
h-index	57
Total Paper Count	184

Publications:

The metalloprotease ADAM10 generates soluble interleukin-2 receptor alpha (sIL-2Rα/sCD25) in vivo.

DOI: 10.1016/j.jbc.2022.101910

Year: 2022

The role of A Disintegrin and Metalloproteinase (ADAM)-10 in T helper cell biology.

DOI: 10.1016/j.bbamcr.2021.119192

Year: 2022

A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4+ T cells and is defective in Crohn´s disease patients.

DOI: 10.1038/s41385-022-00487-x

Year: 2022

A novel unconventional T cell population enriched in Crohn’s disease

DOI: 10.1136/gutjnl-2021-325373

Year: 2022

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

DOI: 10.1002/eji.202170126

Year: 2021

Flow Cytometric Characterization of Human Antigen-Reactive T-Helper Cells.

DOI: 10.1007/978-1-0716-1311-5_12

Year: 2021

Decreased inflammatory cytokine production of antigen-specific CD4+ T cells in NMDA receptor encephalitis

DOI: 10.1007/s00415-020-10371-y

Year: 2021

Characterization of SARS-CoV-2 public CD4+ αβ T cell clonotypes through reverse epitope discovery

DOI: 10.1101/2021.11.19.469229

Year: 2021

Longitudinal multi-omics analysis identifies responses of megakaryocytes, erythroid cells and plasmablasts as hallmarks of severe COVID-19 trajectories

DOI: 10.1101/2020.09.11.20187369

Year: 2020

Pre-existing T cell memory as a risk factor for severe 1 COVID-19 in the elderly

DOI: 10.1101/2020.09.15.20188896

Year: 2020

What is Cell Growth?

How is Glycolysis Linked to Other Metabolic Pathways?

How Does Chromatin Condensation Occur?

Can DNA Fragmentation be Repaired?

How is Chromosome Number Maintained?

How Do Agonistic Antibodies Function?

How Are Antibody-Based Therapies Utilized?

What are the Emerging Discoveries About Astrocytes?

What are the Challenges and Limitations?

How is the Extrinsic Pathway Regulated?

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