4 1bb - Cell Biology

Relevant Publications

Therapeutic potential of co-signaling receptor modulation in hepatitis B.

Issue Release: 2024

4-1BB-encoding CAR causes cell death via sequestration of the ubiquitin-modifying enzyme A20.

Issue Release: 2024

Candidate tumor-specific CD8 T cell subsets identified in the malignant pleural effusion of advanced lung cancer patients by single-cell analysis.

Issue Release: 2024

Development of novel humanized CD19/BAFFR bicistronic chimeric antigen receptor T cells with potent antitumor activity against B-cell lineage neoplasms.

Issue Release: 2024

CD137 (4-1BB) and T-Lymphocyte Exhaustion.

Issue Release: 2024

Batf3 DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy.

Issue Release: 2024

Therapeutic potential of third-generation chimeric antigen receptor T cells targeting B cell maturation antigen for treating multiple myeloma.

Issue Release: 2024

Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics.

Issue Release: 2024

Comparison of seven CD19 CAR designs in engineering NK cells for enhancing anti-tumour activity.

Issue Release: 2024

Characterization of a Trispecific PD-L1 Blocking Antibody That Exhibits EGFR-Conditional 4-1BB Agonist Activity.

Issue Release: 2024

Anti-4-1BB×PD-L1 Bispecific Antibody Reinvigorates Tumor-Specific Exhausted CD8+ T Cells and Enhances the Efficacy of Anti-PD-1 Blockade.

Issue Release: 2024

CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition.

Issue Release: 2024

Identifying immune checkpoints on dysregulated T-cells as prognostic biomarkers for multiple myeloma patients with COVID-19.

Issue Release: 2024

A Comprehensive ddPCR Strategy for Sensitive and Reliable Monitoring of CAR-T Cell Kinetics in Clinical Applications.

Issue Release: 2024

Preclinical characterization and phase 1 results of ADG106 in patients with advanced solid tumors and non-Hodgkin\'s lymphoma.

Issue Release: 2024

Safety and efficacy of nivolumab in elderly patients with metastatic clear cell renal cell carcinoma: Analysis of the NIVOREN GETUG-AFU 26 study.

Issue Release: 2024

OX40/OX40 ligand and its role in precision immune oncology.

Issue Release: 2024

Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies.

Issue Release: 2024

CD19-CD28: An affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy.

Issue Release: 2024

Peritumoral administration of immunomodulatory antibodies as a triple combination suppresses skin tumor growth without systemic toxicity.

Issue Release: 2024

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